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Black box warning for QT interval prolongation and arrhythmias (as a consequence of potassium channel blocking effects). EKG should be monitored carefully for the duration of initiation and dose titration.

Lower hypertension. In case you have reduced blood pressure, hydrocodone could allow it to be even worse. Question your health practitioner no matter whether hydrocodone is Secure for you personally.

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Renal impairment: The producer label isn't going to present dose adjustment guidance for sufferers with renal impairment. On the other hand, 26% of hydrocodone and eighty five% of acetaminophen are eliminated during the urine, And so the drug really should be used with caution.

This medication will bring about constipation. If you don't Have a very bowel movement for 3 days, get in touch with your treatment workforce.

Consider this medication by mouth as directed by your health practitioner. It's possible you'll get this drug with or with out foodstuff. In case you have nausea, it may assist to take this drug with meals.

Difficulty swallowing. Hydrocodone should be swallowed full. Should you have problems swallowing, your medical doctor will likely not prescribe this drug for you personally.

Use in people with elevated intracranial pressure, brain tumors, head personal injury, or impaired consciousness may possibly cut down respiratory generate, and the resultant CO2 retention can further more enhance intracranial force. Use of ROXICODONE should be avoided in sufferers with impaired consciousness or coma.

Your medical professional will explain how you'll want to get hydrocodone, including the amount to consider and how frequently. Be sure to follow your physician’s Directions.

Various normal opioids exist, but You can also find a lot of normal choices that will present equivalent results.

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Combined and partial agonist analgesics: The coadministration of hydrocodone and acetaminophen with other opioid analgesics (eg, butorphanol, nalbuphine, pentazocine) could result in decreasing the analgesic effect of opioids or precipitate withdrawal signs or symptoms.

Prevent ingesting grapefruit or drinking grapefruit juice although working with this medication Except your physician or pharmacist claims chances are you'll do this safely and securely. Grapefruit can improve the potential for Unintended effects with this particular medicine. Check with your health care provider or pharmacist For additional information.

Choose this medication specifically as prescribed to lower the chance of habit. Ask your physician or pharmacist for more aspects.